• Skip to primary navigation
  • Skip to main content
  • Skip to primary sidebar
MRC Laboratory of Molecular Biology

MRC Laboratory of Molecular Biology

One of the world's leading research institutes, our scientists are working to advance understanding of biological processes at the molecular level - providing the knowledge needed to solve key problems in human health.

  • Home
  • About LMB
  • Research
  • Research Groups
  • Students
  • Recruitment
  • Life at the LMB
  • Achievements
  • News & Events
Home > News & Events > Insight on Research

Insight on Research

  • All
  • 2025
  • 2024
  • 2023
  • 2022
  • 2021
  • 2020
  • 2019
  • 2018
  • 2017
  • 2016
  • 2015
  • 2014
  • 2013
  • 2012
  • 2011
  • 2010

Architecture of a prominent neurotransmitter receptor involved in memory formation and learning revealed

AMPA receptors are among the most commonly found receptor in the nervous system and play an important role during memory formation and learning. They are composed of four subunits with various possible combinations. Although AMPA receptors act predominantly as heteromeric complexes, structural studies to date have focused on assemblies made from four copies of the same subunit.

More…

Published on 15th March, 2019

How detection of an invading Salmonella bacterium leads to formation of autophagosomes

Most historical research on immunity has focused on the dedicated cells of our immune system, but, ever since the first single-celled organisms evolved, cells have had to defend themselves against infection. Thus we have a more ancient form of cellular immunity, termed xenophagy, that allows cells throughout our body to capture bacteria that have invaded their cytosol and degrade those invaders inside specialised vesicles termed autophagosomes.

More…

Published on 8th March, 2019

Identification of a potential therapeutic target in colorectal cancer initiation

Colorectal cancer is one of the most common cancers in the UK. Virtually all colorectal cancers are initiated by hyperactive signalling through the Wnt/β-catenin pathway. This can occur due to activating mutations in the protein β-catenin or inactivation of Adenomatous Polyposis Coli (APC), a protein that normally drives degradation of β-catenin.

More…

Published on 13th February, 2019

Engineering dynein to move backwards to understand how it moves forwards

Dyneins are a family of motor proteins that run along the microtubule tracks that make up the cytoskeleton. They drive beating of cilia/flagellar and transport of cargos, contributing to processes such as clearing mucus, allowing sperm to swim, positioning organelles and clearing up misfolded proteins. All members of the family move along microtubules in the same direction, but it was not known why this is the case.

More…

Published on 7th February, 2019

Cutting-edge microscopy reveals how apoptosis starts in the mitochondria

Apoptosis is a highly controlled form of cell death important for cell turnover during life, in embryonic development, including separation of fingers and toes, and as a cellular response against cancer. Although mitochondria are more widely known for their role as the energy-generating “powerhouses” of the cell, they also have an important role in initiating apoptosis: rupture of the mitochondria releases factors that contribute to an accelerating cascade towards cell death.

More…

Published on 6th February, 2019

A master regulator of cell movement in response to chemical signals

Movement of cells is vital during processes such as wound healing and development. Where cells move is usually controlled by gradients of chemicals in the environment that guide them to particular destinations. These attractive chemicals, or chemoattractants, are detected by receptors on the cell surface, which signal to the cytoskeleton to control movement in the appropriate direction.

More…

Published on 4th February, 2019
  • «
  • ‹
  • 3
  • 4
  • 5
  • 6
  • ›

Primary Sidebar

News & Events

  • Insight on Research
  • LMB News
  • LMB In The News
  • LMB Alumni News
  • Public Engagement
    • Supporting Education
      • I’m a scientist, get me out of here!
      • London International Youth Science Forum
    • LMB on the Road
      • Cambridge Festival
      • Royal Society Summer Science Exhibitions
      • Big Biology Day
      • LifeLab
    • Events at the LMB
      • Artists in Residence: Home in the Service of Science
      • LMB Open Day 2017
      • STEM in Song
    • Resources
      • Image Game
    • LMB Science Stories
      • Electron Cryo-microscopy
      • Tau and Alzheimer’s
    • Past Events
      • MRC Festival of Research
      • Crystal Growing Competition
        • Past Winners
        • MRC Lab Visits
      • The WormWatch Lab
    • Contact Us
  • Scientific Seminars
    • LMB Named Lectures
  • LMB Exhibitions
    • Sample holders for electron cryomicroscopy
    • Humira
    • Curios of 60 years of the LMB
  • Scientific Training
  • Information for Journalists
  • Scientific Glossary
  • Photographs
  • LMB 365
  • Newspaper Archive

Search

  • Privacy & Cookies
  • Contact Directory
  • Freedom of Information
  • Site Map
Find Us
©2025 MRC Laboratory of Molecular Biology,
Francis Crick Avenue, Cambridge Biomedical Campus, Cambridge CB2 0QH, UK. 01223 267000

The MRC is part of UK Research and Innovation

Contact Us

This site uses cookies. The LMB may use cookies to analyse how you use our website. We use external analysis systems which may set additional cookies to perform their analysis. These cookies (and any others in use) are detailed in our Privacy and Cookies Policy and are integral to our website. You can delete or disable these cookies in your web browser if you wish, but then our site may not work as it is designed.